Pit Bull Chat Forum

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We are a diverse group of Pit Bull enthusiasts devoted to the preservation of the American Pit Bull Terrier.

Our educational and informational discussion forum about the American Pit Bull Terrier and all other bull breeds is a venue for members to discuss topics, share ideas and come together with the common goal to preserve and promote our canine breed of choice.

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Question: My 4yr old randomly broke out in hives - twice in 4 days.

Hi everyone,

My 4 year old male Pitbull terrier has randomly broken out in hives, twice over the last 4 days. The outbreak lasted roughly 24hrs each time. He takes Apoquel everyday and is updated on shots and vaccinations. He doesn't seem to be bothered by the hives - he does scratch them, bite or paw at them. He doesn't appear to be itching more than normal, yet I have been giving him Benadryl when outbreaks occur.

In the 4 years, he has never had an outbreak even while exploring the woods (NE Ohio). We have not moved/ relocated, changed his diet, nor have we added any new plants/ tree's to our back yard. Not sure what is causing the outbreaks because this has never happened before. (Note: My 2 yr old Shih Tzu is NOT experiencing outbreaks)

Any feedback or recommendation's will be greatly appreciated! :)


Did you ask your vet if taking benedryl and Apoquel is OK? One of mine is on Apoquel, and it has worked great for her hives and rashes. It seems every time the crepe myrtle blooms, she has issues, but I'm really not sure if that's it.
Have you tried the occasional medicated bath for him?